Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers. [electronic resource]
Producer: 20190715Description: 1756-1776 p. digitalISSN:- 1362-4962
- Acetylation
- Cell Line
- Cell Line, Transformed
- Cytostatic Agents -- pharmacology
- Depsipeptides -- pharmacology
- Dose-Response Relationship, Drug
- Enhancer Elements, Genetic -- drug effects
- Genome
- Histone Code -- drug effects
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- physiology
- Histones -- metabolism
- Oncogenes
- Promoter Regions, Genetic
- RNA Polymerase II -- metabolism
- RNA, Messenger -- metabolism
- Thiazoles -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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