Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models. [electronic resource]
Producer: 20050726Description: 2294-301 p. digitalISSN:- 0066-4804
- Animals
- Antitubercular Agents -- administration & dosage
- Colony Count, Microbial
- Disease Models, Animal
- Drug Evaluation, Preclinical
- Female
- Humans
- Lung -- microbiology
- Mice
- Mice, Inbred C57BL
- Microbial Sensitivity Tests
- Mycobacterium tuberculosis -- drug effects
- Nitroimidazoles -- administration & dosage
- Specific Pathogen-Free Organisms
- Spleen -- microbiology
- Tuberculosis, Multidrug-Resistant -- drug therapy
- Tuberculosis, Pulmonary -- drug therapy
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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