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  2. Details for: Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.
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Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase. [electronic resource]

By:
  • Snow, Roger J
Contributor(s):
  • Cardozo, Mario G
  • Morwick, Tina M
  • Busacca, Carl A
  • Dong, Yong
  • Eckner, Robert J
  • Jacober, Stephen
  • Jakes, Scott
  • Kapadia, Suresh
  • Lukas, Susan
  • Panzenbeck, Maret
  • Peet, Gregory W
  • Peterson, Jeffrey D
  • Prokopowicz, Anthony S
  • Sellati, Rosemarie
  • Tolbert, Robert M
  • Tschantz, Matt A
  • Moss, Neil
Producer: 20020819Description: 3394-405 p. digitalISSN:
  • 0022-2623
Subject(s):
  • Animals
  • Antibodies -- pharmacology
  • Binding Sites
  • CD3 Complex -- immunology
  • Crystallography, X-Ray
  • Enzyme Inhibitors -- chemical synthesis
  • Female
  • Humans
  • Imidazoles -- chemical synthesis
  • Interleukin-2 -- biosynthesis
  • Isoquinolines -- chemical synthesis
  • Jurkat Cells
  • Lymphocyte Specific Protein Tyrosine Kinase p56(lck) -- antagonists & inhibitors
  • Mice
  • Mice, Inbred BALB C
  • Models, Molecular
  • Molecular Conformation
  • Structure-Activity Relationship
  • T-Lymphocytes -- drug effects
Online resources:
  • Available from publisher's website
In: Journal of medicinal chemistry vol. 45
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Publication Type: Journal Article

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Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.

APA

Snow R. J., Cardozo M. G., Morwick T. M., Busacca C. A., Dong Y., Eckner R. J., Jacober S., Jakes S., Kapadia S., Lukas S., Panzenbeck M., Peet G. W., Peterson J. D., Prokopowicz A. S., Sellati R., Tolbert R. M., Tschantz M. A. & Moss N. (20020819). Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase. : Journal of medicinal chemistry.

Chicago

Snow Roger J, Cardozo Mario G, Morwick Tina M, Busacca Carl A, Dong Yong, Eckner Robert J, Jacober Stephen, Jakes Scott, Kapadia Suresh, Lukas Susan, Panzenbeck Maret, Peet Gregory W, Peterson Jeffrey D, Prokopowicz Anthony S, Sellati Rosemarie, Tolbert Robert M, Tschantz Matt A and Moss Neil. 20020819. Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase. : Journal of medicinal chemistry.

Harvard

Snow R. J., Cardozo M. G., Morwick T. M., Busacca C. A., Dong Y., Eckner R. J., Jacober S., Jakes S., Kapadia S., Lukas S., Panzenbeck M., Peet G. W., Peterson J. D., Prokopowicz A. S., Sellati R., Tolbert R. M., Tschantz M. A. and Moss N. (20020819). Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase. : Journal of medicinal chemistry.

MLA

Snow Roger J, Cardozo Mario G, Morwick Tina M, Busacca Carl A, Dong Yong, Eckner Robert J, Jacober Stephen, Jakes Scott, Kapadia Suresh, Lukas Susan, Panzenbeck Maret, Peet Gregory W, Peterson Jeffrey D, Prokopowicz Anthony S, Sellati Rosemarie, Tolbert Robert M, Tschantz Matt A and Moss Neil. Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase. : Journal of medicinal chemistry. 20020819.

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