Your search returned 19 results.

Results
	1.	Investigation of MDR1-overexpressing cell lines to derive a quantitative prediction approach for brain disposition using in vitro efflux activities. [electronic resource] by Sato, Sho Tohyama, Kimio Kosugi, Yohei Producer: 20200601 In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences vol. 142 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	2.	Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. [electronic resource] by Tohyama, Kimio Kusuhara, Hiroyuki Sugiyama, Yuichi Producer: 20040928 In: Endocrinology vol. 145 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	3.	Prediction of Human Pharmacokinetic Profile After Transdermal Drug Application Using Excised Human Skin. [electronic resource] by Yamamoto, Syunsuke Karashima, Masatoshi Arai, Yuta Tohyama, Kimio Amano, Nobuyuki Producer: 20180507 In: Journal of pharmaceutical sciences vol. 106 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	4.	Relationship of MATE1 Inhibition and Cytotoxicity in Nephrotoxicity: Application for Safety Evaluation in Early Drug Discovery. [electronic resource] by Tohyama, Kimio Chisaki, Ikumi Takai, Yuichi Handa, Yasuhiro Miyamoto, Makoto Amano, Nobuyuki Producer: 20200724 In: Toxicological sciences : an official journal of the Society of Toxicology vol. 170 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	5.	Fluorescent Imaging Analysis for Distribution of Fluorescent Dye Labeled- or Encapsulated-Liposome in Monocrotaline-Induced Pulmonary Hypertension Model Rat. [electronic resource] by Muraki, Yo Yamasaki, Midori Takeuchi, Hirohisa Tohyama, Kimio Sano, Noriyasu Matsuo, Takanori Producer: 20181010 In: Chemical & pharmaceutical bulletin vol. 66 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	6.	Pre-clinical Characterization of Absorption, Distribution, Metabolism and Excretion Properties of TAK-063. [electronic resource] by Tohyama, Kimio Sudo, Miyako Morohashi, Akio Kato, Suguru Takahashi, Junzo Tagawa, Yoshihiko Producer: 20180927 In: Basic & clinical pharmacology & toxicology vol. 122 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	7.	Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier. [electronic resource] by Ose, Atsushi Kusuhara, Hiroyuki Endo, Chihiro Tohyama, Kimio Miyajima, Mari Kitamura, Satoshi Sugiyama, Yuichi Producer: 20100319 In: Drug metabolism and disposition: the biological fate of chemicals vol. 38 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	8.	Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins. [electronic resource] by Narita, Naohiro Morohashi, Akio Tohyama, Kimio Takeuchi, Toshiyuki Tagawa, Yoshihiko Kondo, Takahiro Asahi, Satoru Producer: 20181017 In: Drug metabolism and disposition: the biological fate of chemicals vol. 46 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	9.	Characterization of binding and inhibitory properties of TAK-063, a novel phosphodiesterase 10A inhibitor. [electronic resource] by Harada, Akina Suzuki, Kazunori Kamiguchi, Naomi Miyamoto, Maki Tohyama, Kimio Nakashima, Kosuke Taniguchi, Takahiko Kimura, Haruhide Producer: 20160223 In: PloS one vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	10.	Utility of Göttingen minipigs for Prediction of Human Pharmacokinetic Profiles After Dermal Drug Application. [electronic resource] by Yamamoto, Syunsuke Karashima, Masatoshi Sano, Noriyasu Fukushi, Chiharu Tohyama, Kimio Arai, Yuta Hirabayashi, Hideki Amano, Nobuyuki Producer: 20180709 In: Pharmaceutical research vol. 34 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	11.	Improvement of pulmonary arterial hypertension, inflammatory response, and epithelium injury by dual activation of cAMP/cGMP pathway in a rat model of monocrotaline-induced pulmonary hypertension. [electronic resource] by Muraki, Yo Naito, Takako Tohyama, Kimio Shibata, Sachio Kuniyeda, Kanako Nio, Yasunori Hazama, Masatoshi Matsuo, Takanori Producer: 20190715 In: Bioscience, biotechnology, and biochemistry vol. 83 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	12.	Fluid shear stress stimulates MATE2-K expression via Nrf2 pathway activation. [electronic resource] by Fukuda, Yasunori Kaishima, Misato Ohnishi, Toshiyuki Tohyama, Kimio Chisaki, Ikumi Nakayama, Yusuke Ogasawara-Shimizu, Mari Kawamata, Yuji Producer: 20170627 In: Biochemical and biophysical research communications vol. 484 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	13.	Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis. [electronic resource] by Amano, Yuichiro Tsuchiya, Shuntarou Imai, Mayumi Tohyama, Kimio Matsukawa, Jun Isono, Osamu Yasuno, Hironobu Enya, Kazuaki Koumura, Emiko Nagabukuro, Hiroshi Producer: 20180316 In: Biochemical and biophysical research communications vol. 497 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	14.	Pharmacokinetic and pharmacodynamic modeling of hedgehog inhibitor TAK-441 for the inhibition of Gli1 messenger RNA expression and antitumor efficacy in xenografted tumor model mice. [electronic resource] by Kogame, Akifumi Tagawa, Yoshihiko Shibata, Sachio Tojo, Hideaki Miyamoto, Maki Tohyama, Kimio Kondo, Takahiro Prakash, Shimoga Shyu, Wen Chyi Asahi, Satoru Producer: 20131104 In: Drug metabolism and disposition: the biological fate of chemicals vol. 41 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	15.	Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and Monkeys. [electronic resource] by Iwasaki, Shinji Yamamoto, Syunsuke Sano, Noriyasu Tohyama, Kimio Kosugi, Yohei Furuta, Atsutoshi Hamada, Teruki Igari, Tomoko Fujioka, Yasushi Hirabayashi, Hideki Amano, Nobuyuki Producer: 20190425 In: Pharmaceutical research vol. 36 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	16.	Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792. [electronic resource] by Sasaki, Masako Miyahisa, Ikuo Itono, Sachiko Yashiro, Hiroaki Hiyoshi, Hideyuki Tsuchimori, Kazue Hamagami, Ken-Ichi Moritoh, Yusuke Watanabe, Masanori Tohyama, Kimio Sasaki, Minoru Sakamoto, Jun-Ichi Kawamoto, Tomohiro Producer: 20200506 In: Pharmacology research & perspectives vol. 7 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	17.	Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury. [electronic resource] by Sisson, Thomas H Christensen, Paul J Muraki, Yo Dils, Anthony J Chibucos, Lauren Subbotina, Natalya Tohyama, Kimio Horowitz, Jeffrey C Matsuo, Takanori Bailie, Marc Nikam, Sham Hazama, Masatoshi Producer: 20190909 In: Physiological reports vol. 6 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	18.	Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium. [electronic resource] by Evers, Raymond Piquette-Miller, Micheline Polli, Joseph W Russel, Frans G M Sprowl, Jason A Tohyama, Kimio Ware, Joseph A de Wildt, Saskia N Xie, Wen Brouwer, Kim L R Producer: 20190924 In: Clinical pharmacology and therapeutics vol. 104 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	19.	Discovery of 3,5-Diphenyl-4-methyl-1,3-oxazolidin-2-ones as Novel, Potent, and Orally Available Δ-5 Desaturase (D5D) Inhibitors. [electronic resource] by Fujimoto, Jun Okamoto, Rei Noguchi, Naoyoshi Hara, Ryoma Masada, Shinichi Kawamoto, Tetsuji Nagase, Hiroki Tamura, Yumiko Okano Imanishi, Mitsuaki Takagahara, Shuichi Kubo, Kazuki Tohyama, Kimio Iida, Koichi Andou, Tomohiro Miyahisa, Ikuo Matsui, Junji Hayashi, Ryouta Maekawa, Tsuyoshi Matsunaga, Nobuyuki Producer: 20171122 In: Journal of medicinal chemistry vol. 60 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)