Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. [electronic resource]
Producer: 20120824Description: 1240-6 p. digitalISSN:- 1098-6596
- Amides -- chemistry
- Animals
- Anti-Bacterial Agents -- chemistry
- Binding Sites
- Crystallography, X-Ray
- DNA Gyrase -- chemistry
- Drug Resistance, Bacterial
- Enzyme Inhibitors -- chemistry
- Humans
- Inhibitory Concentration 50
- Magnetic Resonance Spectroscopy
- Mice
- Microbial Sensitivity Tests
- Models, Molecular
- Mutation
- Protein Binding
- Pyrroles -- chemistry
- Staphylococcal Infections -- drug therapy
- Staphylococcus aureus -- drug effects
- Streptococcus pneumoniae -- drug effects
- Topoisomerase II Inhibitors
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Publication Type: Journal Article
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