Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes. [electronic resource]
Producer: 20150916Description: 64-74 p. digitalISSN:- 2212-4934
- Allosteric Regulation -- drug effects
- Antibiotics, Antineoplastic -- pharmacology
- Catalytic Domain
- Cell Line, Tumor
- Cell Movement
- Cell Survival -- drug effects
- Everolimus
- Glioblastoma -- diet therapy
- Humans
- Immunosuppressive Agents -- pharmacology
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Mitosis
- Multiprotein Complexes -- antagonists & inhibitors
- Phosphatidylinositol 3-Kinases -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Signal Transduction
- Sirolimus -- analogs & derivatives
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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