The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states. [electronic resource]
Producer: 20060207Description: 558-65 p. digitalISSN:- 0006-4971
- Early Growth Response Protein 1 -- metabolism
- Electrophoretic Mobility Shift Assay
- Endothelium, Vascular -- cytology
- Eosinophil Peroxidase -- metabolism
- Eosinophils -- enzymology
- Humans
- Lipopolysaccharides -- pharmacology
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- NF-kappa B -- metabolism
- Oxidants -- pharmacology
- Oxidation-Reduction
- Phagocytes -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- Thiocyanates -- pharmacology
- Thromboplastin -- metabolism
- Thrombosis -- immunology
- Transcription Factor AP-1 -- metabolism
- Transcription Factor RelA -- genetics
- Transcription, Genetic
- Umbilical Veins -- cytology
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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