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LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. [electronic resource] by
- Augustyn, Evan
- Finke, Karissa
- Zur, Arik A
- Hansen, Logan
- Heeren, Nathan
- Chien, Huan-Chieh
- Lin, Lawrence
- Giacomini, Kathleen M
- Colas, Claire
- Schlessinger, Avner
- Thomas, Allen A
Producer: 20170619
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. [electronic resource] by
- Zur, Arik A
- Chien, Huan-Chieh
- Augustyn, Evan
- Flint, Andrew
- Heeren, Nathan
- Finke, Karissa
- Hernandez, Christopher
- Hansen, Logan
- Miller, Sydney
- Lin, Lawrence
- Giacomini, Kathleen M
- Colas, Claire
- Schlessinger, Avner
- Thomas, Allen A
Producer: 20170808
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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6.
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Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors. [electronic resource] by
- Volgraf, Matthew
- Chan, Lina
- Huestis, Malcolm P
- Purkey, Hans E
- Burkard, Michael
- Geck Do, Mary
- Harris, Julie
- Hunt, Kevin W
- Liu, Xingrong
- Lyssikatos, Joseph P
- Rana, Sumeet
- Thomas, Allen A
- Vigers, Guy P A
- Siu, Michael
Producer: 20150102
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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7.
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Prodrug thiamine analogs as inhibitors of the enzyme transketolase. [electronic resource] by
- Le Huerou, Yvan
- Gunawardana, Indrani
- Thomas, Allen A
- Boyd, Steven A
- de Meese, Jason
- Dewolf, Walter
- Gonzales, Steven S
- Han, May
- Hayter, Laura
- Kaplan, Tomas
- Lemieux, Christine
- Lee, Patrice
- Pheneger, Jed
- Poch, Gregory
- Romoff, Todd T
- Sullivan, Francis
- Weiler, Solly
- Wright, S Kirk
- Lin, Jie
Producer: 20080527
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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8.
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Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). [electronic resource] by
- Chien, Huan-Chieh
- Colas, Claire
- Finke, Karissa
- Springer, Seth
- Stoner, Laura
- Zur, Arik A
- Venteicher, Brooklynn
- Campbell, Jerome
- Hall, Colton
- Flint, Andrew
- Augustyn, Evan
- Hernandez, Christopher
- Heeren, Nathan
- Hansen, Logan
- Anthony, Abby
- Bauer, Justine
- Fotiadis, Dimitrios
- Schlessinger, Avner
- Giacomini, Kathleen M
- Thomas, Allen A
Producer: 20191014
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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Mechanistic pharmacokinetic-pharmacodynamic modeling of BACE1 inhibition in monkeys: development of a predictive model for amyloid precursor protein processing. [electronic resource] by
- Liu, Xingrong
- Wong, Harvey
- Scearce-Levie, Kimberly
- Watts, Ryan J
- Coraggio, Melis
- Shin, Young G
- Peng, Kun
- Wildsmith, Kristin R
- Atwal, Jasvinder K
- Mango, Jason
- Schauer, Stephen P
- Regal, Kelly
- Hunt, Kevin W
- Thomas, Allen A
- Siu, Michael
- Lyssikatos, Joseph
- Deshmukh, Gauri
- Hop, Cornelis E C A
Producer: 20131126
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 41
Availability: No items available.
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10.
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Non-charged thiamine analogs as inhibitors of enzyme transketolase. [electronic resource] by
- Thomas, Allen A
- De Meese, J
- Le Huerou, Y
- Boyd, Steven A
- Romoff, Todd T
- Gonzales, Steven S
- Gunawardana, Indrani
- Kaplan, Tomas
- Sullivan, Francis
- Condroski, Kevin
- Lyssikatos, Joseph P
- Aicher, Thomas D
- Ballard, Josh
- Bernat, Bryan
- DeWolf, Walter
- Han, May
- Lemieux, Christine
- Smith, Darin
- Weiler, Solly
- Wright, S Kirk
- Vigers, Guy
- Brandhuber, Barb
Producer: 20080527
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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11.
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Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors. [electronic resource] by
- Thomas, Allen A
- Le Huerou, Y
- De Meese, J
- Gunawardana, Indrani
- Kaplan, Tomas
- Romoff, Todd T
- Gonzales, Stephen S
- Condroski, Kevin
- Boyd, Steven A
- Ballard, Josh
- Bernat, Bryan
- DeWolf, Walter
- Han, May
- Lee, Patrice
- Lemieux, Christine
- Pedersen, Robin
- Pheneger, Jed
- Poch, Greg
- Smith, Darin
- Sullivan, Francis
- Weiler, Solly
- Wright, S Kirk
- Lin, Jie
- Brandhuber, Barb
- Vigers, Guy
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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12.
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8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors. [electronic resource] by
- Thomas, Allen A
- Hunt, Kevin W
- Newhouse, Brad
- Watts, Ryan J
- Liu, Xingrong
- Vigers, Guy
- Smith, Darin
- Rhodes, Susan P
- Brown, Karin D
- Otten, Jennifer N
- Burkard, Michael
- Cox, April A
- Geck Do, Mary K
- Dutcher, Darrin
- Rana, Sumeet
- DeLisle, Robert K
- Regal, Kelly
- Wright, Albion D
- Groneberg, Robert
- Liao, Jiangpeng
- Scearce-Levie, Kimberly
- Siu, Michael
- Purkey, Hans E
- Lyssikatos, Joseph P
Producer: 20150226
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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13.
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Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher species. [electronic resource] by
- Hunt, Kevin W
- Cook, Adam W
- Watts, Ryan J
- Clark, Christopher T
- Vigers, Guy
- Smith, Darin
- Metcalf, Andrew T
- Gunawardana, Indrani W
- Burkard, Michael
- Cox, April A
- Geck Do, Mary K
- Dutcher, Darrin
- Thomas, Allen A
- Rana, Sumeet
- Kallan, Nicholas C
- DeLisle, Robert K
- Rizzi, James P
- Regal, Kelly
- Sammond, Douglas
- Groneberg, Robert
- Siu, Michael
- Purkey, Hans
- Lyssikatos, Joseph P
- Marlow, Allison
- Liu, Xingrong
- Tang, Tony P
Producer: 20130702
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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14.
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Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system. [electronic resource] by
- Thomas, Allen A
- Hunt, Kevin W
- Volgraf, Matthew
- Watts, Ryan J
- Liu, Xingrong
- Vigers, Guy
- Smith, Darin
- Sammond, Douglas
- Tang, Tony P
- Rhodes, Susan P
- Metcalf, Andrew T
- Brown, Karin D
- Otten, Jennifer N
- Burkard, Michael
- Cox, April A
- Do, Mary K Geck
- Dutcher, Darrin
- Rana, Sumeet
- DeLisle, Robert K
- Regal, Kelly
- Wright, Albion D
- Groneberg, Robert
- Scearce-Levie, Kimberly
- Siu, Michael
- Purkey, Hans E
- Lyssikatos, Joseph P
- Gunawardana, Indrani W
Producer: 20140415
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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