Rate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4. [electronic resource]
Producer: 20160125Description: e354 p. digitalISSN:- 2044-5385
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Down-Regulation
- Flow Cytometry
- Gene Knockdown Techniques
- Humans
- Ikaros Transcription Factor -- metabolism
- Immunoblotting
- Immunohistochemistry
- Interferon Regulatory Factors -- metabolism
- Lenalidomide
- Multiple Myeloma -- metabolism
- Proto-Oncogene Proteins c-myc -- metabolism
- RNA, Small Interfering
- Signal Transduction -- drug effects
- Thalidomide -- analogs & derivatives
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.