Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells. [electronic resource]
Producer: 20140312Description: e877 p. digitalISSN:- 2041-4889
- Adenosine Triphosphate -- metabolism
- Amino Acid Oxidoreductases -- genetics
- Animals
- Carrier Proteins -- genetics
- Cell Line, Tumor
- Embryonic Stem Cells -- metabolism
- Energy Metabolism -- drug effects
- Fatty Acids -- biosynthesis
- Female
- Folic Acid -- metabolism
- Gene Expression Regulation, Neoplastic
- Glycine -- metabolism
- Humans
- Male
- Metabolic Flux Analysis
- Metabolic Networks and Pathways
- Methotrexate -- pharmacology
- Mice
- Multienzyme Complexes -- genetics
- NADP -- metabolism
- Neoplasms -- genetics
- Protein Biosynthesis
- Purines -- metabolism
- Serine -- metabolism
- Transferases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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