The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. [electronic resource]
Producer: 20070807Description: 718-32 p. digitalISSN:- 1398-9219
- Animals
- CHO Cells
- Cell Line, Tumor
- Cricetinae
- Cricetulus
- Endoplasmic Reticulum -- metabolism
- Endosomes -- metabolism
- Golgi Apparatus -- metabolism
- Humans
- Hypercholesterolemia -- enzymology
- Lysosomes -- metabolism
- Mutation
- Proprotein Convertase 9
- Proprotein Convertases
- Protein Structure, Tertiary
- Protein Transport
- RNA, Small Interfering -- metabolism
- Receptors, LDL -- metabolism
- Serine Endopeptidases -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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