MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. [electronic resource]
Producer: 20061109Description: 5887-94 p. digitalISSN:- 1078-0432
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Bone Marrow -- pathology
- Cell Adhesion -- drug effects
- Cell Proliferation -- drug effects
- Enzyme Inhibitors
- Humans
- I-kappa B Kinase -- antagonists & inhibitors
- Insulin-Like Growth Factor I -- pharmacology
- Interleukin-6 -- pharmacology
- Mice
- Mice, SCID
- Multiple Myeloma -- drug therapy
- NF-kappa B -- metabolism
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Stromal Cells -- drug effects
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- pharmacology
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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