Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways. [electronic resource]
Producer: 20180604Description: 70-78 p. digitalISSN:- 1873-7544
- Amyloid beta-Peptides -- metabolism
- Animals
- Astrocytes -- drug effects
- Catechin -- analogs & derivatives
- Cell Membrane -- drug effects
- Cells, Cultured
- Cerebral Cortex -- drug effects
- Dose-Response Relationship, Drug
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Extracellular Space -- drug effects
- Isoflavones -- pharmacology
- Neprilysin -- metabolism
- Neuroprotective Agents -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proteolysis -- drug effects
- Rats, Sprague-Dawley
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Publication Type: Journal Article
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