Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration. [electronic resource]
Producer: 20200713Description: 510 p. digitalISSN:- 2041-4889
- Adult
- Aged
- Animals
- Autophagy -- genetics
- Humans
- Immunohistochemistry
- Intervertebral Disc -- metabolism
- Intervertebral Disc Degeneration -- metabolism
- Kelch-Like ECH-Associated Protein 1 -- genetics
- Mice, Inbred C57BL
- Middle Aged
- NF-E2-Related Factor 2 -- genetics
- Nucleus Pulposus -- metabolism
- Oxidation-Reduction
- Oxidative Stress -- genetics
- Real-Time Polymerase Chain Reaction
- Signal Transduction -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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