mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma. [electronic resource]
Producer: 20191212Description: 4669-4684 p. digitalISSN:- 1476-5594
- Active Transport, Cell Nucleus -- genetics
- Animals
- Cell Nucleus -- metabolism
- Cell Proliferation -- genetics
- Cell Transformation, Viral -- physiology
- Cells, Cultured
- Epstein-Barr Virus Infections -- complications
- Glucose -- metabolism
- Glycolysis -- genetics
- Herpesvirus 4, Human -- physiology
- Humans
- Male
- Mechanistic Target of Rapamycin Complex 2 -- physiology
- Mice
- Mice, Inbred NOD
- Mice, Nude
- Mice, SCID
- Nasopharyngeal Carcinoma -- genetics
- Nasopharyngeal Neoplasms -- genetics
- Neoplasm Metastasis
- Protein Transport
- Pyruvate Dehydrogenase (Lipoamide) -- genetics
- Signal Transduction -- genetics
- Viral Matrix Proteins -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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