The phosphatidylinositol 3-kinase signaling pathway exerts protective effects during sepsis by controlling C5a-mediated activation of innate immune functions. [electronic resource]
Producer: 20070618Description: 5940-8 p. digitalISSN:- 0022-1767
- Animals
- Complement C5a -- pharmacology
- Cytokines -- blood
- Humans
- Immunity, Innate
- Lipopolysaccharides -- immunology
- Mice
- Monocytes -- enzymology
- Neutrophils -- drug effects
- Phagocytes -- immunology
- Phagocytosis
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphoinositide-3 Kinase Inhibitors
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Respiratory Burst
- Sepsis -- immunology
- Signal Transduction
- Toll-Like Receptor 4 -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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