Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5. [electronic resource]
Producer: 20090723Description: 778-87 p. digitalISSN:- 1573-675X
- Amino Acid Substitution -- drug effects
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cytochalasin D -- pharmacology
- Humans
- Kinetics
- Mutant Proteins -- metabolism
- Mutation -- genetics
- Paclitaxel -- pharmacology
- Protein Binding -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Surface Plasmon Resonance
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Ultracentrifugation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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