Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. [electronic resource]
Producer: 20030313Description: 476-83 p. digitalISSN:- 0008-5472
- Cell Transformation, Neoplastic -- genetics
- Centrosome -- physiology
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase Inhibitor p16 -- antagonists & inhibitors
- Cyclin-Dependent Kinases -- biosynthesis
- DNA-Binding Proteins
- Gingiva -- cytology
- Humans
- Keratinocytes -- cytology
- Oncogene Proteins, Viral -- biosynthesis
- Papillomavirus E7 Proteins
- Proto-Oncogene Proteins
- Retinoblastoma Protein -- antagonists & inhibitors
- Telomerase -- biosynthesis
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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