Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA. [electronic resource]
Producer: 20040525Description: 625-38 p. digitalISSN:- 0022-2836
- Anti-HIV Agents -- chemistry
- Base Sequence
- Drug Design
- Gene Expression Regulation, Viral
- Gene Products, tat -- genetics
- Guanidines -- chemistry
- HIV-1 -- genetics
- Humans
- Models, Molecular
- Molecular Sequence Data
- Molecular Structure
- Nuclear Magnetic Resonance, Biomolecular
- Nuclear Proteins
- Nucleic Acid Conformation
- Peptides -- metabolism
- Protein Binding
- Protein Conformation
- RNA -- chemistry
- RNA-Binding Proteins -- chemistry
- Structure-Activity Relationship
- tat Gene Products, Human Immunodeficiency Virus
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Publication Type: Journal Article
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