Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465. [electronic resource]
Producer: 20110419Description: 1040-7 p. digitalISSN:- 1600-0625
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Aurora Kinase B
- Aurora Kinases
- Caspase 7 -- metabolism
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Chromosomes, Human -- genetics
- Drug Synergism
- Gene Amplification -- genetics
- HCT116 Cells
- Humans
- Melanoma -- drug therapy
- Neoplastic Stem Cells -- drug effects
- Piperazines -- pharmacology
- Polyploidy
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA, Small Interfering -- genetics
- Tumor Cells, Cultured -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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