7-hydroxyfrullanolide, a sesquiterpene lactone, inhibits pro-inflammatory cytokine production from immune cells and is orally efficacious in animal models of inflammation. [electronic resource]
Producer: 20101207Description: 220-9 p. digitalISSN:- 1879-0712
- Animals
- Anti-Inflammatory Agents -- administration & dosage
- Arthritis, Experimental -- drug therapy
- Arthritis, Rheumatoid -- drug therapy
- Asteraceae -- chemistry
- Colitis -- drug therapy
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Female
- Humans
- Inflammation -- drug therapy
- Inflammation Mediators -- metabolism
- Interleukin-6 -- metabolism
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Rats
- Rats, Wistar
- Sesquiterpenes -- administration & dosage
- Tumor Necrosis Factor-alpha -- drug effects
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Publication Type: Journal Article
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