Ligand-based pharmacophore modeling, atom-based 3D-QSAR and molecular docking studies on substituted thiazoles and thiophenes as polo-like kinase 1 (Plk1) inhibitors. [electronic resource]
Producer: 20150909Description: 848-58 p. digitalISSN:- 1875-5402
- Antineoplastic Agents -- chemistry
- Cell Cycle Proteins -- antagonists & inhibitors
- Drug Design
- Humans
- Molecular Docking Simulation
- Neoplasms -- drug therapy
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Quantitative Structure-Activity Relationship
- Thiazoles -- chemistry
- Thiophenes -- chemistry
- Polo-Like Kinase 1
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Publication Type: Journal Article
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