Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity. [electronic resource]
Producer: 20191105Description: 697 p. digitalISSN:- 2041-4889
- Apoptosis
- Cell Line, Tumor
- Cytosol -- metabolism
- Humans
- Mitochondria -- metabolism
- Molecular Chaperones -- metabolism
- Molecular Docking Simulation
- Mouth Neoplasms -- metabolism
- Oxidative Stress
- Protease La -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Protein Binding
- Protein Stability
- Proteolysis
- Transcription, Genetic
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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