Dual inhibition of the epidermal growth factor receptor with cetuximab, an IgG1 monoclonal antibody, and gefitinib, a tyrosine kinase inhibitor, in patients with refractory non-small cell lung cancer (NSCLC): a phase I study. [electronic resource]
Producer: 20080522Description: 258-64 p. digitalISSN:- 1556-1380
- Aged
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- administration & dosage
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cetuximab
- DNA, Neoplasm -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Female
- Follow-Up Studies
- Gefitinib
- Gene Dosage
- Gene Expression Regulation, Neoplastic
- Humans
- Immunoglobulin G -- immunology
- Immunohistochemistry
- Infusions, Intravenous
- Lung Neoplasms -- drug therapy
- Male
- Middle Aged
- Polymerase Chain Reaction
- Protein Kinase Inhibitors -- administration & dosage
- Quinazolines -- administration & dosage
- Retrospective Studies
- Sequence Analysis, DNA
- Treatment Outcome
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Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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