HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells. [electronic resource]
Producer: 20121126Description: 766-75 p. digitalISSN:- 1555-8576
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- BRCA1 Protein -- genetics
- BRCA2 Protein -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclic S-Oxides -- pharmacology
- Cyclin D1 -- metabolism
- Drug Screening Assays, Antitumor
- Female
- Humans
- Ovarian Neoplasms
- Phosphorylation
- Piperidones -- pharmacology
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- metabolism
- Reactive Oxygen Species -- metabolism
- STAT3 Transcription Factor -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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