Single point mutations in the helicase domain of the NS3 protein enhance dengue virus replicative capacity in human monocyte-derived dendritic cells and circumvent the type I interferon response. [electronic resource]
Producer: 20160620Description: 114-28 p. digitalISSN:- 1365-2249
- Adenosine Triphosphatases -- metabolism
- Cells, Cultured
- Dendritic Cells -- immunology
- Dengue -- immunology
- Dengue Vaccines -- immunology
- Dengue Virus -- physiology
- Humans
- Immune Evasion
- Interferon Type I -- metabolism
- Microarray Analysis
- Monocytes -- immunology
- Point Mutation -- genetics
- Serine Endopeptidases -- genetics
- Virus Replication -- genetics
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Publication Type: Journal Article
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