PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition. [electronic resource]
Producer: 20190101Description: e0200014 p. digitalISSN:- 1932-6203
- Astrocytes -- drug effects
- Carcinogenesis -- drug effects
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- drug effects
- Class I Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
- Drug Synergism
- Enzyme Activation -- drug effects
- Glioblastoma -- etiology
- Humans
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Mutation, Missense
- Protein Kinase Inhibitors -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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