Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. [electronic resource]
Producer: 20160222Description: 283-95 p. digitalISSN:- 1096-0929
- Binding Sites
- Binding, Competitive
- Cell Line
- Drug Discovery -- methods
- Drug-Related Side Effects and Adverse Reactions -- etiology
- Endocrine Disruptors -- chemistry
- Genes, Reporter
- Hormone Antagonists -- chemistry
- Humans
- Ligands
- Models, Molecular
- Protein Binding
- Protein Conformation
- Receptors, Cytoplasmic and Nuclear -- chemistry
- Risk Assessment
- Spectrometry, Fluorescence
- Transfection
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Publication Type: Journal Article
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