Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. [electronic resource]
Producer: 20100409Description: 924-31 p. digitalISSN:- 1524-4563
- 8,11,14-Eicosatrienoic Acid -- metabolism
- Animals
- Cell Nucleus -- metabolism
- Cells, Cultured
- Chemokine CCL2 -- genetics
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- Female
- Fibroblasts -- cytology
- Humans
- Inflammation -- metabolism
- Interleukin-6 -- genetics
- Mice
- NF-kappa B -- metabolism
- RNA, Messenger -- genetics
- Receptor, Angiotensin, Type 2 -- agonists
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Sulfonamides -- pharmacology
- Thiophenes -- pharmacology
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article
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