ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment. [electronic resource]
Producer: 20190625Description: 1156-1166 p. digitalISSN:- 1538-8514
- Administration, Oral
- Animals
- Antineoplastic Agents -- administration & dosage
- Biological Availability
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Humans
- Mice
- Phosphorylation
- Protein Kinase Inhibitors -- administration & dosage
- Xenograft Model Antitumor Assays
- Cyclin-Dependent Kinase-Activating Kinase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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