Results
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Discovery and development of hepatitis C virus NS5A replication complex inhibitors. [electronic resource] by
- Belema, Makonen
- Lopez, Omar D
- Bender, John A
- Romine, Jeffrey L
- St Laurent, Denis R
- Langley, David R
- Lemm, Julie A
- O'Boyle, Donald R
- Sun, Jin-Hua
- Wang, Chunfu
- Fridell, Robert A
- Meanwell, Nicholas A
Producer: 20140515
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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3.
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Novel 3',6'-anhydro and N12,N13-bridged glycosylated fluoroindolo[2,3-a]carbazoles as topoisomerase I inhibitors. Fluorine as a leaving group from sp3 carbon. [electronic resource] by
- Saulnier, Mark G
- Langley, David R
- Frennesson, David B
- Long, Byron H
- Huang, Stella
- Gao, Qi
- Wu, Dedong
- Fairchild, Craig R
- Ruediger, Edward
- Zimmermann, Kurt
- St Laurent, Denis R
- Balasubramanian, Balu N
- Vyas, Dolatrai M
Producer: 20060112
In:
Organic letters vol. 7
Availability: No items available.
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4.
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Sordarin oxazepine derivatives as potent antifungal agents. [electronic resource] by
- Serrano-Wu, Michael H
- St Laurent, Denis R
- Chen, Yijun
- Huang, Stella
- Lam, Kin-Ray
- Matson, James A
- Mazzucco, Charles E
- Stickle, Terry M
- Tully, Thomas P
- Wong, Henry S
- Vyas, Dolatrai M
- Balasubramanian, Balu N
Producer: 20030304
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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5.
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Identification of hepatitis C virus NS5A inhibitors. [electronic resource] by
- Lemm, Julie A
- O'Boyle, Donald
- Liu, Mengping
- Nower, Peter T
- Colonno, Richard
- Deshpande, Milind S
- Snyder, Lawrence B
- Martin, Scott W
- St Laurent, Denis R
- Serrano-Wu, Michael H
- Romine, Jeffrey L
- Meanwell, Nicholas A
- Gao, Min
Producer: 20100121
In:
Journal of virology vol. 84
Availability: No items available.
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6.
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Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes. [electronic resource] by
- Romine, Jeffrey L
- St Laurent, Denis R
- Leet, John E
- Martin, Scott W
- Serrano-Wu, Michael H
- Yang, Fukang
- Gao, Min
- O'Boyle, Donald R
- Lemm, Julie A
- Sun, Jin-Hua
- Nower, Peter T
- Huang, Xiaohua Stella
- Deshpande, Milind S
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 2
Availability: No items available.
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7.
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HCV NS5A replication complex inhibitors. Part 5: discovery of potent and pan-genotypic glycinamide cap derivatives. [electronic resource] by
- Belema, Makonen
- Nguyen, Van N
- St Laurent, Denis R
- Lopez, Omar D
- Qiu, Yuping
- Good, Andrew C
- Nower, Peter T
- Valera, Lourdes
- O'Boyle, Donald R
- Sun, Jin-Hua
- Liu, Mengping
- Fridell, Robert A
- Lemm, Julie A
- Gao, Min
- Knipe, Jay O
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20140124
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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8.
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HCV NS5A replication complex inhibitors. Part 2: investigation of stilbene prolinamides. [electronic resource] by
- St Laurent, Denis R
- Belema, Makonen
- Gao, Min
- Goodrich, Jason
- Kakarla, Ramesh
- Knipe, Jay O
- Lemm, Julie A
- Liu, Mengping
- Lopez, Omar D
- Nguyen, Van N
- Nower, Peter T
- O'Boyle, Donald
- Qiu, Yuping
- Romine, Jeffrey L
- Serrano-Wu, Michael H
- Sun, Jin-Hua
- Valera, Lourdes
- Yang, Fukang
- Yang, Xuejie
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20130204
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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9.
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Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b replicons. [electronic resource] by
- Belema, Makonen
- Nguyen, Van N
- Romine, Jeffrey L
- St Laurent, Denis R
- Lopez, Omar D
- Goodrich, Jason T
- Nower, Peter T
- O'Boyle, Donald R
- Lemm, Julie A
- Fridell, Robert A
- Gao, Min
- Fang, Hua
- Krause, Rudolph G
- Wang, Ying-Kai
- Oliver, A Jayne
- Good, Andrew C
- Knipe, Jay O
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20140515
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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10.
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HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies. [electronic resource] by
- Lopez, Omar D
- Nguyen, Van N
- St Laurent, Denis R
- Belema, Makonen
- Serrano-Wu, Michael H
- Goodrich, Jason T
- Yang, Fukang
- Qiu, Yuping
- Ripka, Amy S
- Nower, Peter T
- Valera, Lourdes
- Liu, Mengping
- O'Boyle, Donald R
- Sun, Jin-Hua
- Fridell, Robert A
- Lemm, Julie A
- Gao, Min
- Good, Andrew C
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20130625
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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11.
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HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activity. [electronic resource] by
- St Laurent, Denis R
- Serrano-Wu, Michael H
- Belema, Makonen
- Ding, Min
- Fang, Hua
- Gao, Min
- Goodrich, Jason T
- Krause, Rudolph G
- Lemm, Julie A
- Liu, Mengping
- Lopez, Omar D
- Nguyen, Van N
- Nower, Peter T
- O'Boyle, Donald R
- Pearce, Bradley C
- Romine, Jeffrey L
- Valera, Lourdes
- Sun, Jin-Hua
- Wang, Ying-Kai
- Yang, Fukang
- Yang, Xuejie
- Meanwell, Nicholas A
- Snyder, Lawrence B
Producer: 20140515
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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12.
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Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model. [electronic resource] by
- Balasubramanian, Balu N
- St Laurent, Denis R
- Saulnier, Mark G
- Long, Byron H
- Bachand, Carol
- Beaulieu, Francis
- Clarke, Wendy
- Deshpande, Milind
- Eummer, Jeffrey
- Fairchild, Craig R
- Frennesson, David B
- Kramer, Robert
- Lee, Frank Y
- Mahler, Mikael
- Martel, Alain
- Naidu, B Narasimhulu
- Rose, William C
- Russell, John
- Ruediger, Edward
- Solomon, Carola
- Stoffan, Karen M
- Wong, Henry
- Wright, John J
- Zimmermann, Kurt
- Vyas, Dolatrai M
Producer: 20040510
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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13.
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Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11. [electronic resource] by
- Saulnier, Mark G
- Balasubramanian, Balu N
- Long, Byron H
- Frennesson, David B
- Ruediger, Edward
- Zimmermann, Kurt
- Eummer, Jeffrey T
- St Laurent, Denis R
- Stoffan, Karen M
- Naidu, B Narasimhulu
- Mahler, Mikael
- Beaulieu, Francis
- Bachand, Carol
- Lee, Frank Y
- Fairchild, Craig R
- Stadnick, Linda K
- Rose, William C
- Solomon, Carola
- Wong, Henry
- Martel, Alain
- Wright, John J
- Kramer, Robert
- Langley, David R
- Vyas, Dolatrai M
Producer: 20050505
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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14.
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Hepatitis C virus NS5A replication complex inhibitors: the discovery of daclatasvir. [electronic resource] by
- Belema, Makonen
- Nguyen, Van N
- Bachand, Carol
- Deon, Dan H
- Goodrich, Jason T
- James, Clint A
- Lavoie, Rico
- Lopez, Omar D
- Martel, Alain
- Romine, Jeffrey L
- Ruediger, Edward H
- Snyder, Lawrence B
- St Laurent, Denis R
- Yang, Fukang
- Zhu, Juliang
- Wong, Henry S
- Langley, David R
- Adams, Stephen P
- Cantor, Glenn H
- Chimalakonda, Anjaneya
- Fura, Aberra
- Johnson, Benjamin M
- Knipe, Jay O
- Parker, Dawn D
- Santone, Kenneth S
- Fridell, Robert A
- Lemm, Julie A
- O'Boyle, Donald R
- Colonno, Richard J
- Gao, Min
- Meanwell, Nicholas A
- Hamann, Lawrence G
Producer: 20140515
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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