Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers. [electronic resource]
Producer: 20070301Description: 1170-5 p. digitalISSN:- 0008-5472
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Humans
- Lapatinib
- PTEN Phosphohydrolase -- deficiency
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Quinazolines -- pharmacology
- Receptor, ErbB-2 -- antagonists & inhibitors
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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