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	1.	Nexus between protein-ligand affinity rank-ordering, biophysical approaches, and drug discovery. [electronic resource] by Spies, M Ashley Producer: 20140605 In: ACS medicinal chemistry letters vol. 4 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	2.	Intrinsic primary and secondary hydrogen kinetic isotope effects for alanine racemase from global analysis of progress curves. [electronic resource] by Spies, M Ashley Toney, Michael D Producer: 20071002 In: Journal of the American Chemical Society vol. 129 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	3.	Flooding enzymes: quantifying the contributions of interstitial water and cavity shape to ligand binding using extended linear response free energy calculations. [electronic resource] by Whalen, Katie L Spies, M Ashley Producer: 20140505 In: Journal of chemical information and modeling vol. 53 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	4.	Multiple hydrogen kinetic isotope effects for enzymes catalyzing exchange with solvent: application to alanine racemase. [electronic resource] by Spies, M Ashley Toney, Michael D Producer: 20030625 In: Biochemistry vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	5.	The trapping of a spontaneously "flipped-out" base from double helical nucleic acids by host-guest complexation with beta-cyclodextrin: the intrinsic base-flipping rate constant for DNA and RNA. [electronic resource] by Spies, M Ashley Schowen, Richard L Producer: 20021231 In: Journal of the American Chemical Society vol. 124 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	6.	Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy. [electronic resource] by Hengel, Sarah R Spies, M Ashley Spies, Maria Producer: 20171025 In: Cell chemical biology vol. 24 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	7.	Allosteric Tuning of Caspase-7: A Fragment-Based Drug Discovery Approach. [electronic resource] by Vance, Nicholas R Gakhar, Lokesh Spies, M Ashley Producer: 20190415 In: Angewandte Chemie (International ed. in English) vol. 56 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	8.	Hybrid Steered Molecular Dynamics-Docking: An Efficient Solution to the Problem of Ranking Inhibitor Affinities Against a Flexible Drug Target. [electronic resource] by Whalen, Katie L Chang, Kevin M Spies, M Ashley Publication details: Molecular informatics May 2011 In: Molecular informatics vol. 30 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	9.	In silico optimization of a fragment-based hit yields biologically active, high-efficiency inhibitors for glutamate racemase. [electronic resource] by Whalen, Katie L Chau, Anthony C Spies, M Ashley Producer: 20151026 In: ChemMedChem vol. 8 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	10.	Biosynthesis of a Novel Glutamate Racemase Containing a Site-Specific 7-Hydroxycoumarin Amino Acid: Enzyme-Ligand Promiscuity Revealed at the Atomistic Level. [electronic resource] by Dean, Sondra F Whalen, Katie L Spies, M Ashley Publication details: ACS central science Oct 2015 In: ACS central science vol. 1 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	11.	Integrating Experimental and In Silico HTS in the Discovery of Inhibitors of Protein-Nucleic Acid Interactions. [electronic resource] by Li, Quinn Folly da Silva Constantino, Laura Spies, M Ashley Producer: 20190305 In: Methods in enzymology vol. 601 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	12.	Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction. [electronic resource] by Subramanyam, Shyamal Jones, William T Spies, Maria Spies, M Ashley Producer: 20131230 In: Nucleic acids research vol. 41 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	13.	Alanine racemase free energy profiles from global analyses of progress curves. [electronic resource] by Spies, M Ashley Woodward, Joshua J Watnik, Mitchell R Toney, Michael D Producer: 20041012 In: Journal of the American Chemical Society vol. 126 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	14.	Nature of allosteric inhibition in glutamate racemase: discovery and characterization of a cryptic inhibitory pocket using atomistic MD simulations and pKa calculations. [electronic resource] by Whalen, Katie L Tussey, Kenneth B Blanke, Steven R Spies, M Ashley Producer: 20110719 In: The journal of physical chemistry. B vol. 115 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	15.	Exploiting Enzyme Plasticity in Virtual Screening: High Efficiency Inhibitors of Glutamate Racemase. [electronic resource] by Whalen, Katie L Pankow, Katherine L Blanke, Steven R Spies, M Ashley Publication details: ACS medicinal chemistry letters Apr 2010 In: ACS medicinal chemistry letters vol. 1 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	16.	Kinetic analysis of the 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. [electronic resource] by Christenson, Steven D Wu, Weiming Spies, M Ashley Shen, Ben Toney, Michael D Producer: 20031210 In: Biochemistry vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	17.	An Atomistic Understanding of Allosteric Inhibition of Glutamate Racemase: a Dampening of Native Activation Dynamics. [electronic resource] by Witkin, Katie R Vance, Nicholas R Caldwell, Colleen Li, Quinn Yu, Liping Spies, M Ashley Producer: 20210208 In: ChemMedChem vol. 15 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	18.	Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles. [electronic resource] by Marsden, Anne E King, Jessica M Spies, M Ashley Kim, Oak K Yahr, Timothy L Producer: 20161213 In: Antimicrobial agents and chemotherapy vol. 60 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	19.	Elucidating the Catalytic Power of Glutamate Racemase by Investigating a Series of Covalent Inhibitors. [electronic resource] by Vance, Nicholas R Witkin, Katie R Rooney, Patrick W Li, Yalan Pope, Marshall Spies, M Ashley Producer: 20190828 In: ChemMedChem vol. 13 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	20.	Determinants of catalytic power and ligand binding in glutamate racemase. [electronic resource] by Spies, M Ashley Reese, Joseph G Dodd, Dylan Pankow, Katherine L Blanke, Steven R Baudry, Jerome Producer: 20090624 In: Journal of the American Chemical Society vol. 131 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)

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Your search returned 26 results.