Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors. [electronic resource]
Producer: 20181127Description: 694-699 p. digitalISSN:- 1464-3405
- Amino Acid Substitution
- Animals
- Benzeneacetamides -- chemical synthesis
- Cell Line, Tumor
- Fluorine Radioisotopes
- Glioma -- metabolism
- Halogenation
- Heterografts
- Humans
- Imidazoles -- chemical synthesis
- Iodine Radioisotopes
- Isocitrate Dehydrogenase -- antagonists & inhibitors
- Mice, Nude
- Muscles -- metabolism
- Mutation
- Radiopharmaceuticals -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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