The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome. [electronic resource]
Producer: 20070531Description: 1083-91 p. digitalISSN:- 0007-0920
- Adult
- Aged
- Aged, 80 and over
- Animals
- Apoptosis
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Movement
- Cystadenocarcinoma, Serous -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Neoplasm Invasiveness
- Ovarian Neoplasms -- metabolism
- Progesterone -- pharmacology
- Progestins -- pharmacology
- RNA, Small Interfering -- therapeutic use
- Receptor, EphB4 -- antagonists & inhibitors
- Survival Rate
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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