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  2. Details for: PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers.
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PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. [electronic resource]

By:
  • Wang, Q
Contributor(s):
  • Liu, P
  • Spangle, J M
  • Von, T
  • Roberts, T M
  • Lin, N U
  • Krop, I E
  • Winer, E P
  • Zhao, J J
Producer: 20170911Description: 3607-12 p. digitalISSN:
  • 1476-5594
Subject(s):
  • Animals
  • Breast Neoplasms -- drug therapy
  • Cell Line, Tumor
  • Cell Survival -- drug effects
  • Class I Phosphatidylinositol 3-Kinases
  • Drug Resistance, Neoplasm -- drug effects
  • Female
  • Humans
  • Lapatinib
  • Mammary Neoplasms, Experimental -- drug therapy
  • Mice, Knockout
  • Molecular Targeted Therapy -- methods
  • PTEN Phosphohydrolase -- deficiency
  • Phosphatidylinositol 3-Kinases -- genetics
  • Phosphoinositide-3 Kinase Inhibitors
  • Protein Kinase Inhibitors -- pharmacology
  • Proto-Oncogene Proteins c-akt -- metabolism
  • Quinazolines -- pharmacology
  • Receptor, ErbB-2 -- antagonists & inhibitors
  • Signal Transduction -- drug effects
  • Thiazoles -- pharmacology
  • Tumor Burden -- drug effects
  • Xenograft Model Antitumor Assays
Online resources:
  • Available from publisher's website
In: Oncogene vol. 35
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Publication Type: Journal Article

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PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers.

APA

Wang Q., Liu P., Spangle J. M., Von T., Roberts T. M., Lin N. U., Krop I. E., Winer E. P. & Zhao J. J. (20170911). PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. : Oncogene.

Chicago

Wang Q, Liu P, Spangle J M, Von T, Roberts T M, Lin N U, Krop I E, Winer E P and Zhao J J. 20170911. PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. : Oncogene.

Harvard

Wang Q., Liu P., Spangle J. M., Von T., Roberts T. M., Lin N. U., Krop I. E., Winer E. P. and Zhao J. J. (20170911). PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. : Oncogene.

MLA

Wang Q, Liu P, Spangle J M, Von T, Roberts T M, Lin N U, Krop I E, Winer E P and Zhao J J. PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. : Oncogene. 20170911.

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