Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor. [electronic resource]
Producer: 20160810Description: 28911-28 p. digitalISSN:- 1949-2553
- Animals
- Carcinoma, Ovarian Epithelial
- Cell Line, Tumor
- Cell Proliferation
- Combined Modality Therapy
- Cytokines -- immunology
- Cytotoxicity, Immunologic
- Electroporation
- Female
- Folate Receptor 1 -- immunology
- Gene Expression Regulation
- Genetic Therapy -- methods
- Humans
- Immunotherapy, Adoptive -- methods
- Lymphocytes, Tumor-Infiltrating -- immunology
- Mice, Inbred NOD
- Mice, SCID
- Neoplasms, Glandular and Epithelial -- genetics
- Ovarian Neoplasms -- genetics
- Phenotype
- RNA -- genetics
- Single-Chain Antibodies -- genetics
- T-Lymphocytes -- immunology
- Time Factors
- Transfection
- Tumor Burden
- Tumor Necrosis Factor Receptor Superfamily, Member 7 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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