Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers. [electronic resource]
Producer: 20190128Description: 3931 p. digitalISSN:- 2041-1723
- Animals
- Apoptosis
- Arachidonate 12-Lipoxygenase -- metabolism
- Arachidonate 5-Lipoxygenase -- metabolism
- Arachidonic Acid
- Calcium -- metabolism
- Coculture Techniques
- HCT116 Cells
- Humans
- Lipid Metabolism
- Metabolome -- drug effects
- Mice
- Mitochondria -- drug effects
- Niclosamide -- pharmacology
- Proton Ionophores -- pharmacology
- Tumor Suppressor Protein p53 -- deficiency
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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