Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activity. [electronic resource]
Producer: 20200827Description: 1591-1604 p. digitalISSN:- 1432-1912
- Animals
- Antihypertensive Agents -- pharmacology
- Antineoplastic Agents -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Proliferation -- drug effects
- Cyclin D1 -- genetics
- Diethylnitrosamine
- Hep G2 Cells
- Humans
- Liver -- drug effects
- Liver Neoplasms -- drug therapy
- MAP Kinase Kinase Kinases -- metabolism
- Male
- Matrix Metalloproteinase 2 -- metabolism
- Mice
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- PPAR gamma -- metabolism
- Telmisartan -- pharmacology
- Transcription Factor RelA -- genetics
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article
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