Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody. [electronic resource]
Producer: 20080523Description: 649-62 p. digitalISSN:- 1460-2105
- Adenocarcinoma -- drug therapy
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Boronic Acids -- pharmacology
- Bortezomib
- Caspase 3 -- metabolism
- Caspase 8 -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Female
- Flow Cytometry
- Humans
- Immunoblotting
- Kidney Neoplasms -- drug therapy
- Lung Neoplasms -- drug therapy
- Mammary Neoplasms, Animal -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mitochondrial Membranes -- metabolism
- Protease Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Pyrazines -- pharmacology
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- agonists
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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