Simian virus 40 large T antigen J domain and Rb-binding motif are sufficient to block apoptosis induced by growth factor withdrawal in a neural stem cell line. [electronic resource]
Producer: 19990824Description: 6791-9 p. digitalISSN:- 0022-538X
- Animals
- Antigens, Polyomavirus Transforming -- metabolism
- Apoptosis
- Binding Sites
- Cell Division
- Cell Line
- Cell Survival
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- metabolism
- Epidermal Growth Factor -- metabolism
- Mice
- Neurons -- cytology
- Nuclear Proteins
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-mdm2
- Retinoblastoma Protein -- metabolism
- Simian virus 40 -- metabolism
- Stem Cells -- cytology
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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