Treatment of type 2 diabetes with the designer cytokine IC7Fc. [electronic resource]
Producer: 20191112Description: 63-68 p. digitalISSN:- 1476-4687
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Binding, Competitive
- Cytokine Receptor gp130 -- metabolism
- Cytokines -- chemical synthesis
- Diabetes Mellitus, Type 2 -- drug therapy
- Drug Design
- Fatty Liver -- prevention & control
- Glucose Tolerance Test
- Humans
- Hyperglycemia -- drug therapy
- Immunoglobulin G -- therapeutic use
- Incretins -- metabolism
- Interleukin-6 -- antagonists & inhibitors
- Male
- Mice
- Muscle, Skeletal -- drug effects
- Obesity -- metabolism
- Pancreas -- metabolism
- Phosphoproteins -- metabolism
- Protein Engineering
- Receptors, Interleukin-6 -- metabolism
- Recombinant Fusion Proteins -- therapeutic use
- Signal Transduction
- Transcription Factors
- Weight Gain -- drug effects
- YAP-Signaling Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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