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Novel 5-cyclopropyl-1,4-benzodiazepin-2-ones as potent and selective I(Ks)-blocking class III antiarrhythmic agents. [electronic resource] by
- Butcher, John W
- Liverton, Nigel J
- Claremon, David A
- Freidinger, Roger M
- Jurkiewicz, Nancy K
- Lynch, Joseph J
- Salata, Joseph J
- Wang, Jixin
- Dieckhaus, Christine M
- Slaughter, Donald E
- Vyas, Kamlesh
Producer: 20031027
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP. [electronic resource] by
- Cox, Christopher D
- Torrent, Maricel
- Breslin, Michael J
- Mariano, Brenda J
- Whitman, David B
- Coleman, Paul J
- Buser, Carolyn A
- Walsh, Eileen S
- Hamilton, Kelly
- Schaber, Michael D
- Lobell, Robert B
- Tao, Weikang
- South, Vicki J
- Kohl, Nancy E
- Yan, Youwei
- Kuo, Lawrence C
- Prueksaritanont, Thomayant
- Slaughter, Donald E
- Li, Chunze
- Mahan, Elizabeth
- Lu, Bing
- Hartman, George D
Producer: 20060816
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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4.
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Kinesin spindle protein (KSP) inhibitors. Part 3: synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility. [electronic resource] by
- Garbaccio, Robert M
- Fraley, Mark E
- Tasber, Edward S
- Olson, Christy M
- Hoffman, William F
- Arrington, Kenneth L
- Torrent, Maricel
- Buser, Carolyn A
- Walsh, Eileen S
- Hamilton, Kelly
- Schaber, Michael D
- Fernandes, Christine
- Lobell, Robert B
- Tao, Weikang
- South, Vicki J
- Yan, Youwei
- Kuo, Lawrence C
- Prueksaritanont, Thomayant
- Slaughter, Donald E
- Shu, Cathy
- Heimbrook, David C
- Kohl, Nancy E
- Huber, Hans E
- Hartman, George D
Producer: 20060719
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP. [electronic resource] by
- Garbaccio, Robert M
- Tasber, Edward S
- Neilson, Lou Anne
- Coleman, Paul J
- Fraley, Mark E
- Olson, Christy
- Bergman, Jeff
- Torrent, Maricel
- Buser, Carolyn A
- Rickert, Keith
- Walsh, Eileen S
- Hamilton, Kelly
- Lobell, Robert B
- Tao, Weikang
- South, Vicki J
- Diehl, Ronald E
- Davide, Joseph P
- Yan, Youwei
- Kuo, Lawrence C
- Li, Chunze
- Prueksaritanont, Thomayant
- Fernandez-Metzler, Carmen
- Mahan, Elizabeth A
- Slaughter, Donald E
- Salata, Joseph J
- Kohl, Nancy E
- Huber, Hans E
- Hartman, George D
Producer: 20071212
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer. [electronic resource] by
- Cox, Christopher D
- Coleman, Paul J
- Breslin, Michael J
- Whitman, David B
- Garbaccio, Robert M
- Fraley, Mark E
- Buser, Carolyn A
- Walsh, Eileen S
- Hamilton, Kelly
- Schaber, Michael D
- Lobell, Robert B
- Tao, Weikang
- Davide, Joseph P
- Diehl, Ronald E
- Abrams, Marc T
- South, Vicki J
- Huber, Hans E
- Torrent, Maricel
- Prueksaritanont, Thomayant
- Li, Chunze
- Slaughter, Donald E
- Mahan, Elizabeth
- Fernandez-Metzler, Carmen
- Yan, Youwei
- Kuo, Lawrence C
- Kohl, Nancy E
- Hartman, George D
Producer: 20080829
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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