Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells. [electronic resource]
Producer: 20010111Description: 6607-10 p. digitalISSN:- 0008-5472
- Animals
- Anticarcinogenic Agents -- pharmacology
- Caco-2 Cells
- Clone Cells
- Colonic Neoplasms -- drug therapy
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- pharmacology
- Dinoprostone -- biosynthesis
- Genes, ras -- drug effects
- Humans
- Isoenzymes -- antagonists & inhibitors
- Membrane Proteins
- Mice
- Mice, SCID
- Prostaglandin-Endoperoxide Synthases -- biosynthesis
- Sulindac -- analogs & derivatives
- Transfection
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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