The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. [electronic resource]
Producer: 20010510Description: 3369-72 p. digitalISSN:- 0008-5472
- 2-Methoxyestradiol
- Angiogenesis Inhibitors -- antagonists & inhibitors
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents, Phytogenic -- antagonists & inhibitors
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Docetaxel
- Drug Synergism
- Endothelial Growth Factors -- immunology
- Endothelium, Vascular -- cytology
- Estradiol -- analogs & derivatives
- Fibroblast Growth Factor 2 -- physiology
- Humans
- Lymphokines -- immunology
- Mice
- Mice, Nude
- Neovascularization, Physiologic -- drug effects
- Paclitaxel -- analogs & derivatives
- Taxoids
- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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