The antiapoptotic gene A1/BFL1 is a WT1 target gene that mediates granulocytic differentiation and resistance to chemotherapy. [electronic resource]
Producer: 20060814Description: 4695-702 p. digitalISSN:- 0006-4971
- Animals
- Cell Differentiation -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Granulocyte Colony-Stimulating Factor -- biosynthesis
- Granulocyte Precursor Cells -- cytology
- Humans
- Interleukin-3 -- pharmacology
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Minor Histocompatibility Antigens
- Myelopoiesis -- drug effects
- NIH 3T3 Cells
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Up-Regulation -- drug effects
- WT1 Proteins -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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