Phase I Study of Topotecan, Ifosfamide, and Etoposide (TIME) with autologous stem cell transplant in refractory cancer: pharmacokinetic and pharmacodynamic correlates. [electronic resource]
Producer: 20120611Description: 7743-53 p. digitalISSN:- 1557-3265
- Adult
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Area Under Curve
- Combined Modality Therapy -- statistics & numerical data
- DNA Topoisomerases, Type I -- blood
- Drug Administration Schedule
- Drug Resistance, Neoplasm
- Etoposide -- administration & dosage
- Female
- Hematopoietic Stem Cell Transplantation -- methods
- Humans
- Ifosfamide -- administration & dosage
- Kaplan-Meier Estimate
- Male
- Mesna -- administration & dosage
- Metabolic Clearance Rate
- Middle Aged
- Mucositis -- chemically induced
- Multivariate Analysis
- Neoplasms -- blood
- Proportional Hazards Models
- Topotecan -- administration & dosage
- Transplantation, Autologous
- Treatment Outcome
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
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