Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation. [electronic resource]
Producer: 20080815Description: 1439-49 p. digitalISSN:- 1439-7633
- Amino Acid Sequence
- Bacterial Proteins -- chemistry
- Catalysis
- Enzyme Stability
- Gene Expression Regulation, Bacterial
- Heme -- metabolism
- Humans
- Hydroxylation
- Models, Molecular
- Molecular Sequence Data
- Mutant Proteins -- chemistry
- Mutation
- Oxidation-Reduction
- Progesterone -- chemistry
- Protein Structure, Tertiary
- Recombinant Proteins -- chemistry
- Sequence Alignment
- Sequence Homology, Amino Acid
- Stereoisomerism
- Steroid Hydroxylases -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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