Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C [electronic resource]
Producer: 20170627Description: 496-500 p. digitalISSN:- 1464-3405
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Pyrimidines -- chemical synthesis
- Solubility
- Structure-Activity Relationship
- fms-Like Tyrosine Kinase 3 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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