Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells. [electronic resource]
Producer: 20190903Description: 112-120 p. digitalISSN:- 1872-7980
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis
- Carcinoma, Lewis Lung -- drug therapy
- Caspase 3 -- genetics
- Cell Cycle
- Cell Proliferation
- Cisplatin -- administration & dosage
- Drug Synergism
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Lung Neoplasms -- drug therapy
- Male
- Mice
- Mice, Inbred C57BL
- Poly (ADP-Ribose) Polymerase-1 -- genetics
- Polysaccharides -- administration & dosage
- Toll-Like Receptor 4 -- genetics
- Transcription Factor CHOP -- genetics
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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